Engineering/project | LOWENCO

Proven across global biopharma environments

Supporting infrastructure at leading pharmaceutical production and CDMO sites

• Experience spanning high-regulation environments

• Delivered across North America, EU and Asia

• Trusted in facilities where operational continuity is critical

Our project experience spans both new facility developments and extensions to existing sites, enabling engineering teams to rely on established delivery practices rather than untested approaches.

Proven reliability

A LOWENCO solution is engineered with fully redundant critical components, helping ensure temperature stability even in the event of individual component failure.

This design philosophy supports continuous operation in environments where downtime can have significant operational consequences.

Reliability, in this context, is engineered into the infrastructure and not addressed reactively.

Quality that supports long-term operation

LOWENCO freezer shells are engineered for a structural lifespan exceeding 25 years, while critical components are designed to be replaceable, allowing our solution to evolve without requiring full reinvestment.

To support long-term operational continuity, we has established local service teams across the U.S., Europe, and Asia, ensuring proximity to critical environments and enabling responsive technical support throughout the system lifecycle.

This serviceable architecture, combined with regional support, helps protect capital investments and provides engineering teams with confidence that infrastructure will remain supported as operational demands evolve.

Energy performance as a strategic partner

As operational energy demands increase, engineering teams are placing greater emphasis on infrastructure efficiency to support long-term facility resilience.

LOWENCO solutions are engineered to deliver measurable performance improvements, including:

• Up to 66% lower energy consumption
• Up to 98% reduction in HVAC requirements
• Up to 76% lower total cost of ownership over a 25-year lifecycle

These modeled outcomes reflect the compounding impact of energy optimization across decades of operation

Accountability across project phases

Complex infrastructure projects benefit from clearly defined responsibility structures.

LOWENCO operates through a turnkey delivery model, providing engineering teams with a single accountable partner across planning, construction, installation and commissioning.

This centralized approach helps reduce coordination complexity, streamline communication and support more predictable project execution.

Clear accountability is ultimately a mechanism for risk reduction.

TRADITIONAL INTEGRATED ULT storage

Best suited for facilities with lower storage volumes, less temperature-sensitive materials and limited long-term expansion plans, where a straightforward multi-freezer setup can meet operational requirements.

Storage capacity is typically around 200-400 kg/L per unit, meaning multiple individual freezers are often required to reach the desired storage volume
With more units, facilities must allocate larger floorspace for spacing, servicing and HVAC support, creating a more complex layout over time
Each freezer operates independently, meaning the system have higher overall energy consumption, with no shared efficiencies between units
Traditional panel cooling delivers less uniform airflow due to older engineering principles and the way products are tightly packed inside the freezer, which limits circulation around each product
The cooling design and inventory configuration lead to extended temperature recovery following door openings.
With multiple standalone freezers and no shared redundancy, system stability often depends on backup solutions

Ideal for +3,000 kg/L Storage

purpose-built LArge-scale ULT Storage

Ideal for organizations handling highly sensitive biologics, expecting significant future growth or needing centralized, efficient and scalable ULT infrastructure designed for long-term performance.

Purpose-built systems offer storage capacities up to 4,800 kg/L per unit, enabling much higher output per square meter
With fewer larger freezers, facilities can achieve a more compact footprint, using up to 75% less floorspace compared to multiple standalone freezers
The integrated storage solution operate at a system level, rather than per unit and therefore delivers up to 80% lower energy consumption
The entire storage solution is engineered with forced airflow design, ensuring uniform temperature control around every stored item - even when the storage volume is high
The advanced cooling technology and the inventory design increase the temperature recovery time
The system architecture incorporates built-in redundancy, allowing the storage environment to remain stable without relying on external backup solutions

How lifecycle performance is engineered

Designed for decades. Supported throughout the lifecycle

Inputs til video speak:

Core Topics the Video Must Convey

Infrastructure — not equipment: cold storage decisions impact operations for decades.
Lifecycle performance is engineered at the design stage, not solved through maintenance later.
Structural durability: freezer shells designed for 25+ years of operation.
Replaceable architecture: critical components can be exchanged without full system reinvestment.
Built for adaptability as regulatory, technological, and capacity requirements evolve.
Energy efficiency as a long-term financial lever — performance that compounds over time.
Lower lifecycle cost driven by reduced energy demand and optimized infrastructure design.
Regional lifecycle support across the U.S., Europe, and Asia to ensure long-term operational continuity.
Designed to reduce future operational risk and protect infrastructure investment.
A partner engineered for long-horizon reliability — not short-term delivery.